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Checkpoints and Early Embryogenesis
University of California
Santa Cruz,
United States,
Languages:
English
Type:
Academic
Categories:
Biology, Cell Biology, Life Science, Molecular Biology
Brief Description:
Recently we discovered that DNA damage produces a Chk1/Grp dependent delay in metaphase.
Detail Description:

Recently we discovered that DNA damage produces a Chk1/Grp dependent delay in metaphase.  This result is surprising because DNA damage checkpoints were thought to act specifically in interphase and the spindle assembly checkpoint during metaphase. 

Royou, A., H. Macias, and W. Sullivan 2005  Grp/Chk1 delays anaphase onset in response to DNA damage.  Current Biology 15: 334-339. 

Fasulo, B. and W. Sullivan. (2006)  Live analysis of precisely timed drug injections in the Drosophila embryo.  Methods in Molecular Biology, Confocal Microscopy Methods and Protocols.  Edited by S. Paddock.


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Contact Information:
Prof. William T. Sullivan
Phone: (831) 459-3402
Fax:
E-Mail: Sullivan@biology.ucsc.edu
URL:
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